The Lancet· Martha A Q Curley, Martin C J Kneyber, Ira M Cheifetz, Michele Kong, Sidharth Mahapatra, Adam J Schwarz, Suwannee Phumeetham, Katherine Irby, Natalie Napolitano, Onella S Dawkins-Henry, Emily E Birch, Corrine F Elliott, Lindsay R Berry, Kevin J Downes, Aruna Natarajan, Michelle A Detry, Kert Viele, Todd L Graves, Michael Matthay, Lisa A Asaro, David Wypij, PROSpect Study Investigators, Paediatric Acute Lung Injury and Sepsis Investigators Network·· 37 分钟前AI 评分56
PROSpect III 期试验：俯卧位与高频振荡通气未改善早期儿童 ARDS 无呼吸机天数
[Articles] Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect): an international, two-by-two factorial, response-adaptive, phase 3, randomised controlled trial
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PROSpect 国际 II×II 析因、应答适应性 III 期随机对照试验未发现证据支持将俯卧位或高频振荡通气（HFOV）作为早期中重度儿童急性呼吸窘迫综合征（PARDS）的一线策略来改善无呼吸机天数。研究因此不建议在该人群中常规使用这两种策略。
来源：The Lancet · thelancet.com